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A Convergent Total Synthesis of the Potent Cephalostatin/Ritterazine Hybrid -25-epi Ritterostatin G(N)1(N)

The convergent synthesis of 25-epi ritterostatin G(N)1(N) is described for the first time, starting from hecogenin acetate (HA). Stereoselective dihydroxylation employing the chiral ligand (DHQ)(2)PHAL was used as the key step to introduce the C25 epi-stereocenter on the north 1 segment. The title c...

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Detaylı Bibliyografya
Yayımlandı:J Org Chem
Asıl Yazarlar: Kanduluru, Ananda Kumar, Banerjee, Prabal, Beutler, John A, Fuchs, Philip L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511990/
https://ncbi.nlm.nih.gov/pubmed/23899273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo401171q
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