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Inhibition of radiation-induced skin fibrosis with imatinib
PURPOSE: Dermal fibrosis is a disabling late toxicity of radiotherapy. Several lines of evidence suggest that overactive signaling via the Platelet-derived growth factor receptor-beta (PDGFR-β) and V-abl Abelson murine leukemia viral oncogene homolog 1 (cAbl) may be etiologic factors in the developm...
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| Publicado no: | Int J Radiat Biol |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7511984/ https://ncbi.nlm.nih.gov/pubmed/23083077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/09553002.2013.741281 |
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