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Transforming Growth Factor Alpha is a Critical Mediator of Radiation Lung Injury
Radiation fibrosis of the lung is a late toxicity of thoracic irradiation. Epidermal growth factor (EGF) signaling has previously been implicated in radiation lung injury. We hypothesized that TGF-α, an EGF receptor ligand, plays a key role in radiation-induced fibrosis in lung. Mice deficient in tr...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4169125/ https://ncbi.nlm.nih.gov/pubmed/25117621 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR13625.1 |
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