Translation elongation factor 2 depletion by siRNA in mouse liver leads to mTOR-independent translational upregulation of ribosomal protein genes

Due to breakthroughs in RNAi and genome editing methods in the past decade, it is now easier than ever to study fine details of protein synthesis in animal models. However, most of our understanding of translation comes from unicellular organisms and cultured mammalian cells. In this study, we demon...

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Detaylı Bibliyografya
Yayımlandı:Sci Rep
Asıl Yazarlar: Gerashchenko, Maxim V., Nesterchuk, Mikhail V., Smekalova, Elena M., Paulo, Joao A., Kowalski, Piotr S., Akulich, Kseniya A., Bogorad, Roman, Dmitriev, Sergey E., Gygi, Steven, Zatsepin, Timofei, Anderson, Daniel G., Gladyshev, Vadim N., Koteliansky, Victor E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511953/
https://ncbi.nlm.nih.gov/pubmed/32968084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72399-4
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