Glutathionylated and Fe–S cluster containing hMIA40 (CHCHD4) regulates ROS and mitochondrial complex III and IV activities of the electron transport chain

Human MIA40, an intermembrane space (IMS) import receptor of mitochondria harbors twin CX9C motifs for stability while its CPC motif is known to facilitate the import of IMS bound proteins. Site-directed mutagenesis complemented by MALDI on in vivo hMIA40 protein shows that a portion of MIA40 underg...

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Vydáno v:Redox Biol
Hlavní autoři: Thiriveedi, Venkata Ramana, Mattam, Ushodaya, Pattabhi, Prasad, Bisoyi, Vandana, Talari, Noble Kumar, Krishnamoorthy, Thanuja, Sepuri, Naresh Babu V.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2020
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511737/
https://ncbi.nlm.nih.gov/pubmed/32971361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101725
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