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A conserved R type Methionine Sulfoxide Reductase reverses oxidized GrpEL1/Mge1 to regulate Hsp70 chaperone cycle

Cells across evolution employ reversible oxidative modification of methionine and cysteine amino acids within proteins to regulate responses to redox stress. Previously we have shown that mitochondrial localized methionine sulfoxide reductase (Mxr2) reversibly regulates oxidized yeast Mge1 (yMge1),...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Allu, Praveen Kumar, Boggula, Yerranna, Karri, Srinivasu, Marada, Adinarayana, Krishnamoorthy, Thanuja, Sepuri, Naresh Babu V.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807549/
https://ncbi.nlm.nih.gov/pubmed/29426933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21083-9
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