A conserved R type Methionine Sulfoxide Reductase reverses oxidized GrpEL1/Mge1 to regulate Hsp70 chaperone cycle

Cells across evolution employ reversible oxidative modification of methionine and cysteine amino acids within proteins to regulate responses to redox stress. Previously we have shown that mitochondrial localized methionine sulfoxide reductase (Mxr2) reversibly regulates oxidized yeast Mge1 (yMge1),...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Sci Rep
Prif Awduron: Allu, Praveen Kumar, Boggula, Yerranna, Karri, Srinivasu, Marada, Adinarayana, Krishnamoorthy, Thanuja, Sepuri, Naresh Babu V.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group UK 2018
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807549/
https://ncbi.nlm.nih.gov/pubmed/29426933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21083-9
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