Mge1, a nucleotide exchange factor of Hsp70, acts as an oxidative sensor to regulate mitochondrial Hsp70 function

Despite the growing evidence of the role of oxidative stress in disease, its molecular mechanism of action remains poorly understood. The yeast Saccharomyces cerevisiae provides a valuable model system in which to elucidate the effects of oxidative stress on mitochondria in higher eukaryotes. Dimeri...

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Bibliographic Details
Main Authors: Marada, Adinarayana, Allu, Praveen Kumar, Murari, Anjaneyulu, PullaReddy, BhoomiReddy, Tammineni, Prasad, Thiriveedi, Venkata Ramana, Danduprolu, Jayasree, Sepuri, Naresh Babu V.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3596242/
https://ncbi.nlm.nih.gov/pubmed/23345595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E12-10-0719
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