Glutathionylated and Fe–S cluster containing hMIA40 (CHCHD4) regulates ROS and mitochondrial complex III and IV activities of the electron transport chain

Human MIA40, an intermembrane space (IMS) import receptor of mitochondria harbors twin CX9C motifs for stability while its CPC motif is known to facilitate the import of IMS bound proteins. Site-directed mutagenesis complemented by MALDI on in vivo hMIA40 protein shows that a portion of MIA40 underg...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Thiriveedi, Venkata Ramana, Mattam, Ushodaya, Pattabhi, Prasad, Bisoyi, Vandana, Talari, Noble Kumar, Krishnamoorthy, Thanuja, Sepuri, Naresh Babu V.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511737/
https://ncbi.nlm.nih.gov/pubmed/32971361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2020.101725
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