Comparison of CRISPR/Cas Endonucleases for in vivo Retinal Gene Editing

CRISPR/Cas has opened the prospect of direct gene correction therapy for some inherited retinal diseases. Previous work has demonstrated the utility of adeno-associated virus (AAV) mediated delivery to retinal cells in vivo; however, with the expanding repertoire of CRISPR/Cas endonucleases, it is n...

Full description

Saved in:
Bibliographic Details
Published in:Front Cell Neurosci
Main Authors: Li, Fan, Wing, Kristof, Wang, Jiang-Hui, Luu, Chi D., Bender, James A., Chen, Jinying, Wang, Qi, Lu, Qinyi, Nguyen Tran, Minh Thuan, Young, Kaylene M., Wong, Raymond C. B., Pébay, Alice, Cook, Anthony L., Hung, Sandy S. C., Liu, Guei-Sheung, Hewitt, Alex W.
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2020
Subjects:
Neuroscience
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511709/
https://ncbi.nlm.nih.gov/pubmed/33132845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2020.570917
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items