Primary breast tumours but not lung metastases induce protective anti-tumour immune responses after Treg-depletion

Although metastatic disease is responsible for the majority of cancer deaths, tests of novel immunotherapies in mouse tumour models often focus on primary tumours without determining whether these therapies also target metastatic disease. This study examined the impact of depleting Foxp3(+) regulato...

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Publicado en:Cancer Immunol Immunother
Autores principales: Hughes, Ellyn, Lauder, Sarah N., Smart, Kathryn, Bloom, Anja, Scott, Jake, Jones, Emma, Somerville, Michelle, Browne, Molly, Blainey, Andrew, Godkin, Andrew, Ager, Ann, Gallimore, Awen
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Berlin Heidelberg 2020
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511476/
https://ncbi.nlm.nih.gov/pubmed/32447412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02603-x
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