Primary breast tumours but not lung metastases induce protective anti-tumour immune responses after Treg-depletion

Although metastatic disease is responsible for the majority of cancer deaths, tests of novel immunotherapies in mouse tumour models often focus on primary tumours without determining whether these therapies also target metastatic disease. This study examined the impact of depleting Foxp3(+) regulato...

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Bibliografische gegevens
Gepubliceerd in:Cancer Immunol Immunother
Hoofdauteurs: Hughes, Ellyn, Lauder, Sarah N., Smart, Kathryn, Bloom, Anja, Scott, Jake, Jones, Emma, Somerville, Michelle, Browne, Molly, Blainey, Andrew, Godkin, Andrew, Ager, Ann, Gallimore, Awen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer Berlin Heidelberg 2020
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Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511476/
https://ncbi.nlm.nih.gov/pubmed/32447412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02603-x
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