Primary breast tumours but not lung metastases induce protective anti-tumour immune responses after Treg-depletion

Although metastatic disease is responsible for the majority of cancer deaths, tests of novel immunotherapies in mouse tumour models often focus on primary tumours without determining whether these therapies also target metastatic disease. This study examined the impact of depleting Foxp3(+) regulato...

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Detalhes bibliográficos
Publicado no:Cancer Immunol Immunother
Main Authors: Hughes, Ellyn, Lauder, Sarah N., Smart, Kathryn, Bloom, Anja, Scott, Jake, Jones, Emma, Somerville, Michelle, Browne, Molly, Blainey, Andrew, Godkin, Andrew, Ager, Ann, Gallimore, Awen
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7511476/
https://ncbi.nlm.nih.gov/pubmed/32447412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00262-020-02603-x
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