Three-dimensional Imaging Reveals Immune-driven Tumor-associated High Endothelial Venules as a Key Correlate of Tumor Rejection Following Depletion of Regulatory T Cells

High endothelial venules (HEV) are specialized post capillary venules that recruit naïve T cells and B cells into secondary lymphoid organs (SLO) such as lymph nodes (LN). Expansion of HEV networks in SLOs occurs following immune activation to support development of an effective immune response. In...

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Publicat a:Cancer Res Commun
Autors principals: Milutinovic, Stefan, Abe, Jun, Jones, Emma, Kelch, Inken, Smart, Kathryn, Lauder, Sarah N., Somerville, Michelle, Ware, Carl, Godkin, Andrew, Stein, Jens V., Bogle, Gib, Gallimore, Awen
Format: Artigo
Idioma:Inglês
Publicat: American Association for Cancer Research 2022
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7614106/
https://ncbi.nlm.nih.gov/pubmed/36704666
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2767-9764.CRC-21-0123
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