A novel vitamin D gene therapy for acute myeloid leukemia

Current treatment approaches for older adult patients with acute myeloid leukemia (AML) are often toxic and lack efficacy. Active vitamin D3 (1,25(OH)(2)D3) has been shown to induce myeloid blast differentiation but at concentrations that have resulted in unacceptable, off-target hypercalcemia in cl...

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Dades bibliogràfiques
Publicat a:Transl Oncol
Autors principals: Xu, Yi, Payne, Kimberly, Pham, Linh Hoang Gia, Eunwoo, Park, Xiao, Jeffrey, Chi, David, Lyu, Justin, Campion, Rosalia, Wasnik, Samiksha, Jeong, Il Seok, Tang, Xiaolei, Baylink, David Jeston, Chen, Chien Shing, Reeves, Mark, Akhtari, Mojtaba, Mirshahidi, Saied, Marcucci, Guido, Cao, Huynh
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press 2020
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7509076/
https://ncbi.nlm.nih.gov/pubmed/32956997
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100869
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