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Discovery of proangiogenic CD44+mesenchymal cancer stem cells in an acute myeloid leukemia patient’s bone marrow

Here, we report a unique acute myeloid leukemia (AML) bone marrow-derived mesenchymal stem cell (MSC) with both mesenchymal and endothelial potential, which we have named Mesenchymal Cancer Stem Cells (MCSCs). These MCSCs are CD90-CD13-CD44+ and differ from MSCs in isolation, expansion, differentiat...

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Detalhes bibliográficos
Publicado no:J Hematol Oncol
Main Authors: Cao, Huynh, Xiao, Jeffrey, Reeves, Mark E., Payne, Kimberly, Chen, Chien Shing, Baylink, David J., Marcucci, Guido, Xu, Yi
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7268388/
https://ncbi.nlm.nih.gov/pubmed/32493379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-020-00899-x
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