IL-33-ST2 axis regulates myeloid cell differentiation and activation enabling effective club cell regeneration

Evidence points to an indispensable function of macrophages in tissue regeneration, yet the underlying molecular mechanisms remain elusive. Here we demonstrate a protective function for the IL-33-ST2 axis in bronchial epithelial repair, and implicate ST2 in myeloid cell differentiation. ST2 deficien...

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Detaylı Bibliyografya
Yayımlandı:Nat Commun
Asıl Yazarlar: Dagher, Rania, Copenhaver, Alan M., Besnard, Valerie, Berlin, Aaron, Hamidi, Fatima, Maret, Marielle, Wang, Jingya, Qu, Xiaotao, Shrestha, Yashaswi, Wu, Jincheng, Gautier, Gregory, Raja, Rajiv, Aubier, Michel, Kolbeck, Roland, Humbles, Alison A., Pretolani, Marina
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2020
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7508874/
https://ncbi.nlm.nih.gov/pubmed/32963227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-18466-w
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