Lung Chitinolytic Activity and Chitotriosidase Are Elevated in Chronic Obstructive Pulmonary Disease and Contribute to Lung Inflammation

Chronic obstructive pulmonary disease (COPD) is characterized by chronic airway inflammation and emphysematous alveolar destruction. In this study, we have investigated whether chitotriosidase (ChTRase) and acidic mammalian chitinase, two chitinases with chitinolytic activity, are selectively augmen...

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Detalhes bibliográficos
Main Authors: Létuvé, Séverine, Kozhich, Alexander, Humbles, Alison, Brewah, Yambasu, Dombret, Marie-Christine, Grandsaigne, Martine, Adle, Homa, Kolbeck, Roland, Aubier, Michel, Coyle, Anthony J., Pretolani, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2010
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808072/
https://ncbi.nlm.nih.gov/pubmed/20042671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090455
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