Lung Chitinolytic Activity and Chitotriosidase Are Elevated in Chronic Obstructive Pulmonary Disease and Contribute to Lung Inflammation

Chronic obstructive pulmonary disease (COPD) is characterized by chronic airway inflammation and emphysematous alveolar destruction. In this study, we have investigated whether chitotriosidase (ChTRase) and acidic mammalian chitinase, two chitinases with chitinolytic activity, are selectively augmen...

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Autors principals: Létuvé, Séverine, Kozhich, Alexander, Humbles, Alison, Brewah, Yambasu, Dombret, Marie-Christine, Grandsaigne, Martine, Adle, Homa, Kolbeck, Roland, Aubier, Michel, Coyle, Anthony J., Pretolani, Marina
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2010
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808072/
https://ncbi.nlm.nih.gov/pubmed/20042671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090455
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