Lung Chitinolytic Activity and Chitotriosidase Are Elevated in Chronic Obstructive Pulmonary Disease and Contribute to Lung Inflammation

Chronic obstructive pulmonary disease (COPD) is characterized by chronic airway inflammation and emphysematous alveolar destruction. In this study, we have investigated whether chitotriosidase (ChTRase) and acidic mammalian chitinase, two chitinases with chitinolytic activity, are selectively augmen...

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Hlavní autoři: Létuvé, Séverine, Kozhich, Alexander, Humbles, Alison, Brewah, Yambasu, Dombret, Marie-Christine, Grandsaigne, Martine, Adle, Homa, Kolbeck, Roland, Aubier, Michel, Coyle, Anthony J., Pretolani, Marina
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2010
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2808072/
https://ncbi.nlm.nih.gov/pubmed/20042671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.090455
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