Inflammatory triggers associated with exacerbations of COPD orchestrate plasticity of group 2 innate lymphoid cells in the lungs

Innate lymphoid cells (ILCs) are critical mediators of mucosal immunity, and group 1 ILCs (ILC1 cells) and group 3 ILCs (ILC3 cells) have been shown to be functionally plastic. Here we found that group 2 ILCs (ILC2 cells) also exhibited phenotypic plasticity in response to infectious or noxious agen...

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Publicado no:Nat Immunol
Main Authors: Silver, Jonathan S, Kearley, Jennifer, Copenhaver, Alan M, Sanden, Caroline, Mori, Michiko, Yu, Li, Pritchard, Gretchen Harms, Berlin, Aaron A, Hunter, Christopher A, Bowler, Russell, Erjefalt, Jonas S, Kolbeck, Roland, Humbles, Alison A
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5345745/
https://ncbi.nlm.nih.gov/pubmed/27111143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.3443
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