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Osteopontin That Is Elevated in the Airways during COPD Impairs the Antibacterial Activity of Common Innate Antibiotics

Bacterial infections of the respiratory tract contribute to exacerbations and disease progression in chronic obstructive pulmonary disease (COPD). There is also an increased risk of invasive pneumococcal disease in COPD. The underlying mechanisms are not fully understood but include impaired mucocil...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gela, Anele, Bhongir, Ravi K. V., Mori, Michiko, Keenan, Paul, Mörgelin, Matthias, Erjefält, Jonas S., Herwald, Heiko, Egesten, Arne, Kasetty, Gopinath
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712133/
https://ncbi.nlm.nih.gov/pubmed/26731746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146192
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