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Osteopontin That Is Elevated in the Airways during COPD Impairs the Antibacterial Activity of Common Innate Antibiotics

Bacterial infections of the respiratory tract contribute to exacerbations and disease progression in chronic obstructive pulmonary disease (COPD). There is also an increased risk of invasive pneumococcal disease in COPD. The underlying mechanisms are not fully understood but include impaired mucocil...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Gela, Anele, Bhongir, Ravi K. V., Mori, Michiko, Keenan, Paul, Mörgelin, Matthias, Erjefält, Jonas S., Herwald, Heiko, Egesten, Arne, Kasetty, Gopinath
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4712133/
https://ncbi.nlm.nih.gov/pubmed/26731746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0146192
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