Osteopontin Expression in Small Airway Epithelium in Copd is Dependent on Differentiation and Confined to Subsets of Cells

Osteopontin (OPN) plays a role in inflammation via recruitment of neutrophils and tissue remodeling. In this study, we investigated the distribution of OPN-expressing cells in the airway epithelium of normal lung tissue and that from patients with chronic obstructive pulmonary disease (COPD). OPN wa...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ali, Mohamad N., Mori, Michiko, Mertens, Tinne C. J., Siddhuraj, Premkumar, Erjefält, Jonas S., Önnerfjord, Patrik, Hiemstra, Pieter S., Egesten, Arne
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6820743/
https://ncbi.nlm.nih.gov/pubmed/31664154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-52208-3
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