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Formicamycin biosynthesis involves a unique reductive ring contraction

Fasamycin natural products are biosynthetic precursors of the formicamycins. Both groups of compounds are polyketide natural products that exhibit potent antibacterial activity despite displaying different three-dimensional topologies. We show here that transformation of fasamycin into formicamycin...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Qin, Zhiwei, Devine, Rebecca, Booth, Thomas J., Farrar, Elliot H. E., Grayson, Matthew N., Hutchings, Matthew I., Wilkinson, Barrie
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504897/
https://ncbi.nlm.nih.gov/pubmed/33033611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0sc01712d
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