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A role for antibiotic biosynthesis monooxygenase domain proteins in fidelity control during aromatic polyketide biosynthesis

The formicamycin biosynthetic gene cluster encodes two groups of type 2 polyketide antibiotics: the formicamycins and their biosynthetic precursors the fasamycins, both of which have activity against methicillin-resistant Staphylococcus aureus. Here, we report the formicapyridines which are encoded...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Qin, Zhiwei, Devine, Rebecca, Hutchings, Matthew I., Wilkinson, Barrie
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6689052/
https://ncbi.nlm.nih.gov/pubmed/31399587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11538-6
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