B Cell αv Integrins Regulate TLR-Driven Autoimmunity

Systemic lupus erythematosus (SLE) is defined by loss of B cell tolerance, resulting in production of autoantibodies against nucleic acids and other cellular Ags. Aberrant activation of TLRs by self-derived RNA and DNA is strongly associated with SLE in patients and in mouse models, but the mechanis...

Full description

Saved in:
Bibliographic Details
Published in:J Immunol
Main Authors: Acharya, Mridu, Raso, Fiona, Sagadiev, Sara, Gilbertson, Emily, Kadavy, Lauren, Li, Quan Z., Yan, Mei, Stuart, Lynda M., Hamerman, Jessica A., Lacy-Hulbert, Adam
Format: Artigo
Language:Inglês
Published: AAI 2020
Subjects:
Immune Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504890/
https://ncbi.nlm.nih.gov/pubmed/32859730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901056
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items