B Cell αv Integrins Regulate TLR-Driven Autoimmunity

Systemic lupus erythematosus (SLE) is defined by loss of B cell tolerance, resulting in production of autoantibodies against nucleic acids and other cellular Ags. Aberrant activation of TLRs by self-derived RNA and DNA is strongly associated with SLE in patients and in mouse models, but the mechanis...

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Bibliografski detalji
Izdano u:J Immunol
Glavni autori: Acharya, Mridu, Raso, Fiona, Sagadiev, Sara, Gilbertson, Emily, Kadavy, Lauren, Li, Quan Z., Yan, Mei, Stuart, Lynda M., Hamerman, Jessica A., Lacy-Hulbert, Adam
Format: Artigo
Jezik:Inglês
Izdano: AAI 2020
Teme:
Immune Regulation
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504890/
https://ncbi.nlm.nih.gov/pubmed/32859730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1901056
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