α(v) Integrins regulate germinal center B cell responses through noncanonical autophagy

Germinal centers (GCs) are major sites of clonal B cell expansion and generation of long-lived, high-affinity antibody responses to pathogens. Signaling through TLRs on B cells promotes many aspects of GC B cell responses, including affinity maturation, class switching, and differentiation into long...

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Pubblicato in:J Clin Invest
Autori principali: Raso, Fiona, Sagadiev, Sara, Du, Samuel, Gage, Emily, Arkatkar, Tanvi, Metzler, Genita, Stuart, Lynda M., Orr, Mark T., Rawlings, David J., Jackson, Shaun W., Lacy-Hulbert, Adam, Acharya, Mridu
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2018
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118577/
https://ncbi.nlm.nih.gov/pubmed/29999501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI99597
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