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BAFF promotes autoantibody production via TACI-dependent activation of transitional B cells
Mice overexpressing B cell activating factor of the TNF family (BAFF) develop systemic autoimmunity characterized by class-switched anti-nuclear antibodies. Transmembrane activator and CAML interactor (TACI) signals are critical for BAFF-mediated autoimmunity, but the B cell developmental subsets un...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4868625/ https://ncbi.nlm.nih.gov/pubmed/27022196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1600017 |
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