αv Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice

Th17 cells are a distinct lineage of T helper cells that protect the body from bacterial and fungal infection. However, Th17 cells also contribute to inflammatory and autoimmune disorders such as multiple sclerosis. Th17 cell generation requires exposure of naive T cells to the cytokine TGF-β in com...

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Detalhes bibliográficos
Main Authors: Acharya, Mridu, Mukhopadhyay, Subhankar, Païdassi, Helena, Jamil, Tahseen, Chow, Camille, Kissler, Stephan, Stuart, Lynda M., Hynes, Richard O., Lacy-Hulbert, Adam
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993596/
https://ncbi.nlm.nih.gov/pubmed/21099114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI43796
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