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GANT61 and Lithium Chloride Inhibit the Growth of Head and Neck Cancer Cell Lines Through the Regulation of GLI3 Processing by GSK3β

Several signaling pathways are aberrantly activated in head and neck squamous cell carcinoma (HNSCC), including the Hedgehog-Gli (HH-GLI), WNT, EGFR, and NOTCH pathways. The HH-GLI pathway has mostly been investigated in the context of canonical signal transduction and the inhibition of the membrane...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Zubčić, Vedran, Rinčić, Nikolina, Kurtović, Matea, Trnski, Diana, Musani, Vesna, Ozretić, Petar, Levanat, Sonja, Leović, Dinko, Sabol, Maja
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504345/
https://ncbi.nlm.nih.gov/pubmed/32899202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176410
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