GANT61 and Lithium Chloride Inhibit the Growth of Head and Neck Cancer Cell Lines Through the Regulation of GLI3 Processing by GSK3β

Several signaling pathways are aberrantly activated in head and neck squamous cell carcinoma (HNSCC), including the Hedgehog-Gli (HH-GLI), WNT, EGFR, and NOTCH pathways. The HH-GLI pathway has mostly been investigated in the context of canonical signal transduction and the inhibition of the membrane...

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Détails bibliographiques
Publié dans:Int J Mol Sci
Auteurs principaux: Zubčić, Vedran, Rinčić, Nikolina, Kurtović, Matea, Trnski, Diana, Musani, Vesna, Ozretić, Petar, Levanat, Sonja, Leović, Dinko, Sabol, Maja
Format: Artigo
Langue:Inglês
Publié: MDPI 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504345/
https://ncbi.nlm.nih.gov/pubmed/32899202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176410
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