Combination of Cyclopamine and Tamoxifen Promotes Survival and Migration of MCF-7 Breast Cancer Cells – Interaction of Hedgehog-Gli and Estrogen Receptor Signaling Pathways

Hedgehog-Gli (Hh-Gli) signaling pathway is one of the new molecular targets found upregulated in breast tumors. Estrogen receptor alpha (ERα) signaling has a key role in the development of hormone-dependent breast cancer. We aimed to investigate the effects of inhibiting both pathways simultaneously...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Sabol, Maja, Trnski, Diana, Uzarevic, Zvonimir, Ozretic, Petar, Musani, Vesna, Rafaj, Maja, Cindric, Mario, Levanat, Sonja
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4264763/
https://ncbi.nlm.nih.gov/pubmed/25503972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114510
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