GANT61 and Lithium Chloride Inhibit the Growth of Head and Neck Cancer Cell Lines Through the Regulation of GLI3 Processing by GSK3β

Several signaling pathways are aberrantly activated in head and neck squamous cell carcinoma (HNSCC), including the Hedgehog-Gli (HH-GLI), WNT, EGFR, and NOTCH pathways. The HH-GLI pathway has mostly been investigated in the context of canonical signal transduction and the inhibition of the membrane...

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Veröffentlicht in:Int J Mol Sci
Hauptverfasser: Zubčić, Vedran, Rinčić, Nikolina, Kurtović, Matea, Trnski, Diana, Musani, Vesna, Ozretić, Petar, Levanat, Sonja, Leović, Dinko, Sabol, Maja
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2020
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7504345/
https://ncbi.nlm.nih.gov/pubmed/32899202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms21176410
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