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Why TDP-43? Why Not? Mechanisms of Metabolic Dysfunction in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a rapidly progressive and fatal neurodegenerative disorder for which there is no effective curative treatment available and minimal palliative care. Mutations in the gene encoding the TAR DNA-binding protein 43 (TDP-43) are a well-recognized genetic cause of AL...

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Détails bibliographiques
Publié dans:Neurosci Insights
Auteurs principaux: Floare, Mara-Luciana, Allen, Scott P.
Format: Artigo
Langue:Inglês
Publié: SAGE Publications 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7503004/
https://ncbi.nlm.nih.gov/pubmed/32995749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/2633105520957302
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