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An autoregulatory switch in sex-specific phf7 transcription causes loss of sexual identity and tumors in the Drosophila female germline

Maintenance of germ cell sexual identity is essential for reproduction. Entry into the spermatogenesis or oogenesis pathway requires that the appropriate gene network is activated and the antagonist network is silenced. For example, in Drosophila female germ cells, forced expression of the testis-sp...

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Библиографические подробности
Опубликовано в: :Development
Главные авторы: Smolko, Anne E., Shapiro-Kulnane, Laura, Salz, Helen K.
Формат: Artigo
Язык:Inglês
Опубликовано: The Company of Biologists Ltd 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502600/
https://ncbi.nlm.nih.gov/pubmed/32816970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.192856
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