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Maintenance of Drosophila germline stem cell sexual identity in oogenesis and tumorigenesis
Adult stem cells maintain tissue homeostasis by balancing self-renewal and differentiation. In Drosophila females, germline stem cells (GSCs) require Sex lethal (Sxl) to exit the stem cell state and to enter the differentiation pathway. Without Sxl GSCs do not differentiate and instead form tumors....
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| Publicado no: | Development |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4360176/ https://ncbi.nlm.nih.gov/pubmed/25758221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.116590 |
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