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Maintenance of Drosophila germline stem cell sexual identity in oogenesis and tumorigenesis

Adult stem cells maintain tissue homeostasis by balancing self-renewal and differentiation. In Drosophila females, germline stem cells (GSCs) require Sex lethal (Sxl) to exit the stem cell state and to enter the differentiation pathway. Without Sxl GSCs do not differentiate and instead form tumors....

詳細記述

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書誌詳細
出版年:Development
主要な著者: Shapiro-Kulnane, Laura, Smolko, Anne Elizabeth, Salz, Helen Karen
フォーマット: Artigo
言語:Inglês
出版事項: The Company of Biologists 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4360176/
https://ncbi.nlm.nih.gov/pubmed/25758221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.116590
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