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An autoregulatory switch in sex-specific phf7 transcription causes loss of sexual identity and tumors in the Drosophila female germline

Maintenance of germ cell sexual identity is essential for reproduction. Entry into the spermatogenesis or oogenesis pathway requires that the appropriate gene network is activated and the antagonist network is silenced. For example, in Drosophila female germ cells, forced expression of the testis-sp...

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Detalhes bibliográficos
Publicado no:Development
Main Authors: Smolko, Anne E., Shapiro-Kulnane, Laura, Salz, Helen K.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502600/
https://ncbi.nlm.nih.gov/pubmed/32816970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.192856
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