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Sex-lethal enables germline stem cell differentiation by down-regulating Nanos protein levels during Drosophila oogenesis

Drosophila ovarian germ cells require Sex-lethal (Sxl) to exit from the stem cell state and to enter the differentiation pathway. Sxl encodes a female-specific RNA binding protein and in somatic cells serves as the developmental switch gene for somatic sex determination and X-chromosome dosage compe...

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Bibliografski detalji
Glavni autori: Chau, Johnnie, Kulnane, Laura Shapiro, Salz, Helen K.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386055/
https://ncbi.nlm.nih.gov/pubmed/22645327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120473109
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