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Sex-lethal enables germline stem cell differentiation by down-regulating Nanos protein levels during Drosophila oogenesis
Drosophila ovarian germ cells require Sex-lethal (Sxl) to exit from the stem cell state and to enter the differentiation pathway. Sxl encodes a female-specific RNA binding protein and in somatic cells serves as the developmental switch gene for somatic sex determination and X-chromosome dosage compe...
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| Principais autores: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3386055/ https://ncbi.nlm.nih.gov/pubmed/22645327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120473109 |
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