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Sex-lethal enables germline stem cell differentiation by down-regulating Nanos protein levels during Drosophila oogenesis

Drosophila ovarian germ cells require Sex-lethal (Sxl) to exit from the stem cell state and to enter the differentiation pathway. Sxl encodes a female-specific RNA binding protein and in somatic cells serves as the developmental switch gene for somatic sex determination and X-chromosome dosage compe...

詳細記述

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書誌詳細
主要な著者: Chau, Johnnie, Kulnane, Laura Shapiro, Salz, Helen K.
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386055/
https://ncbi.nlm.nih.gov/pubmed/22645327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1120473109
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