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Inhibition of acid ceramidase regulates MHC class II antigen presentation and suppression of autoimmune arthritis
The bioactive sphingolipid ceramide affects immune responses although its effect on antigen (Ag) processing and delivery by HLA class II to CD4+ T-cells remains unclear. Therefore, we examined the actions of a novel cell-permeable acid ceramidase (AC) inhibitor [(1R,2R) N myristoylamino-(4′-nitrophe...
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| Publicado no: | Cytokine |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7502491/ https://ncbi.nlm.nih.gov/pubmed/32738771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2020.155219 |
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