Constitutively active androgen receptor supports the metastatic phenotype of endocrine-resistant hormone receptor-positive breast cancer

BACKGROUND: Hormone receptor positive (HR+) breast cancer (BCa) is the most frequently diagnosed subtype. Acquired and intrinsic resistance to conventional endocrine therapy (ET) commonly occurs and prompts incurable metastatic disease. Hence, ET-resistant (ET-R) HR+ BCa presents a therapeutic chall...

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Detalhes bibliográficos
Publicado no:Cell Commun Signal
Main Authors: Bahnassy, Shaymaa, Thangavel, Hariprasad, Quttina, Maram, Khan, Ashfia Fatima, Dhanyalayam, Dhanya, Ritho, Joan, Karami, Samaneh, Ren, Jing, Bawa-Khalfe, Tasneem
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501670/
https://ncbi.nlm.nih.gov/pubmed/32948192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12964-020-00649-z
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