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Variation in the UGT2B17 genotype, exemestane metabolism and menopause-related toxicities in the CCTG MAP.3 trial

PURPOSE: To examine associations between the UGT2B17 gene deletion and exemestane metabolites, and commonly reported side-effects (fatigue, hot flashes, and joint pain) among postmenopausal women participating in the MAP.3 chemoprevention trial. METHODS: The analytical samples for the UGT2B17 analys...

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Detalhes bibliográficos
Publicado no:Breast Cancer Res Treat
Main Authors: Ho, Vikki, Pasquet, Romain, Luo, Shaman, Chen, Gang, Goss, Paul, Tu, Dongsheng, Lazarus, Philip, Richardson, Harriet
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501182/
https://ncbi.nlm.nih.gov/pubmed/32715442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-020-05812-1
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