Envelope Protein Ubiquitination Drives Zika Virus Entry and Pathogenesis

Zika virus (ZIKV) belongs to the Flaviviridae family and is related to other viruses that cause human diseases. Unlike other flaviviruses, ZIKV infection can cause congenital neurologic disorders and replicates efficiently in reproductive tissues(1–3,). Here, we show that ZIKV envelope (E) protein i...

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Publicado no:Nature
Main Authors: Giraldo, Maria I., Xia, Hongjie, Aguilera-Aguirre, Leopoldo, Hage, Adam, van Tol, Sarah, Shan, Chao, Xie, Xuping, Sturdevant, Gail L., Robertson, Shelly J., McNally, Kristin L., Meade-White, Kimberly, Azar, Sasha R., Rossi, Shannan L., Maury, Wendy, Woodson, Michael, Ramage, Holly, Johnson, Jeffrey R., Krogan, Nevan J., Morais, Marc C., Best, Sonja M., Shi, Pei-Yong, Rajsbaum, Ricardo
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501154/
https://ncbi.nlm.nih.gov/pubmed/32641828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2457-8
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