Envelope Protein Ubiquitination Drives Zika Virus Entry and Pathogenesis

Zika virus (ZIKV) belongs to the Flaviviridae family and is related to other viruses that cause human diseases. Unlike other flaviviruses, ZIKV infection can cause congenital neurologic disorders and replicates efficiently in reproductive tissues(1–3,). Here, we show that ZIKV envelope (E) protein i...

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Vydáno v:Nature
Hlavní autoři: Giraldo, Maria I., Xia, Hongjie, Aguilera-Aguirre, Leopoldo, Hage, Adam, van Tol, Sarah, Shan, Chao, Xie, Xuping, Sturdevant, Gail L., Robertson, Shelly J., McNally, Kristin L., Meade-White, Kimberly, Azar, Sasha R., Rossi, Shannan L., Maury, Wendy, Woodson, Michael, Ramage, Holly, Johnson, Jeffrey R., Krogan, Nevan J., Morais, Marc C., Best, Sonja M., Shi, Pei-Yong, Rajsbaum, Ricardo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501154/
https://ncbi.nlm.nih.gov/pubmed/32641828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2457-8
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