Envelope Protein Ubiquitination Drives Zika Virus Entry and Pathogenesis

Zika virus (ZIKV) belongs to the Flaviviridae family and is related to other viruses that cause human diseases. Unlike other flaviviruses, ZIKV infection can cause congenital neurologic disorders and replicates efficiently in reproductive tissues(1–3,). Here, we show that ZIKV envelope (E) protein i...

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Gepubliceerd in:Nature
Hoofdauteurs: Giraldo, Maria I., Xia, Hongjie, Aguilera-Aguirre, Leopoldo, Hage, Adam, van Tol, Sarah, Shan, Chao, Xie, Xuping, Sturdevant, Gail L., Robertson, Shelly J., McNally, Kristin L., Meade-White, Kimberly, Azar, Sasha R., Rossi, Shannan L., Maury, Wendy, Woodson, Michael, Ramage, Holly, Johnson, Jeffrey R., Krogan, Nevan J., Morais, Marc C., Best, Sonja M., Shi, Pei-Yong, Rajsbaum, Ricardo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501154/
https://ncbi.nlm.nih.gov/pubmed/32641828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2457-8
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