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Structural insights into ADP-ribosylation of ubiquitin by Deltex family E3 ubiquitin ligases

Cellular cross-talk between ubiquitination and other posttranslational modifications contributes to the regulation of numerous processes. One example is ADP-ribosylation of the carboxyl terminus of ubiquitin by the E3 DTX3L/ADP-ribosyltransferase PARP9 heterodimer, but the mechanism remains elusive....

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Pubblicato in:Sci Adv
Autori principali: Chatrin, Chatrin, Gabrielsen, Mads, Buetow, Lori, Nakasone, Mark A., Ahmed, Syed F., Sumpton, David, Sibbet, Gary J., Smith, Brian O., Huang, Danny T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Association for the Advancement of Science 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7500938/
https://ncbi.nlm.nih.gov/pubmed/32948590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc0418
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