DELTEX2 C-terminal domain recognizes and recruits ADP-ribosylated proteins for ubiquitination

Cross-talk between ubiquitination and ADP-ribosylation regulates spatiotemporal recruitment of key players in many signaling pathways. The DELTEX family ubiquitin ligases (DTX1 to DTX4 and DTX3L) are characterized by a RING domain followed by a C-terminal domain (DTC) of hitherto unknown function. H...

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Veröffentlicht in:Sci Adv
Hauptverfasser: Ahmed, Syed Feroj, Buetow, Lori, Gabrielsen, Mads, Lilla, Sergio, Chatrin, Chatrin, Sibbet, Gary J., Zanivan, Sara, Huang, Danny T.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Association for the Advancement of Science 2020
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Research Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7442474/
https://ncbi.nlm.nih.gov/pubmed/32937373
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.abc0629
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