mGluR5 hypofunction is integral to glutamatergic dysregulation in schizophrenia

Multiple lines of evidence point to glutamatergic signaling in the postsynaptic density (PSD) as a pathophysiologic mechanism in schizophrenia. Integral to PSD glutamatergic signaling is reciprocal interplay between GluN and mGluR5 signaling. We examined agonist-induced mGluR5 signaling in the postm...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Psychiatry
Main Authors: Wang, Hoau-Yan, MacDonald, Mathew L., Borgmann-Winter, Karin E., Banerjee, Anamika, Sleiman, Patrick, Tom, Andrew, Khan, Amber, Lee, Kuo-Chieh, Roussos, Panos, Siegel, Steven J., Hemby, Scott E, Bilker, Warren B., Gur, Raquel E., Hahn, Chang-Gyu
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7500805/
https://ncbi.nlm.nih.gov/pubmed/30214040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41380-018-0234-y
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados