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Group I mGluR-induced Epileptogenesis: Distinct and Overlapping Roles of mGluR1 and mGluR5 and Implications for Antiepileptic Drug Design

The group I metabotropic glutamate receptor subtypes, mGluR1 and mGluR5, have both distinct and overlapping actions in epileptogenesis. Data are reviewed revealing how activation of these receptor subtypes participates in the induction and maintenance of the long-lasting epileptiform discharges elic...

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Detalles Bibliográficos
Main Authors: Wong, Robert K.S., Bianchi, Riccardo, Chuang, Shih-Chieh, Merlin, Lisa R.
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1176311/
https://ncbi.nlm.nih.gov/pubmed/16059439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1535-7597.2005.05207.x
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