Učitavanje...

Nucleosomes effectively shield DNA from radiation damage in living cells

Eukaryotic DNA is organized in nucleosomes, which package DNA and regulate its accessibility to transcription, replication, recombination and repair. Here, we show that in living cells nucleosomes protect DNA from high-energy radiation and reactive oxygen species. We combined sequence-based methods...

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Bibliografski detalji
Izdano u:Nucleic Acids Res
Glavni autori: Brambilla, Francesca, Garcia-Manteiga, Jose Manuel, Monteleone, Emanuele, Hoelzen, Lena, Zocchi, Angelica, Agresti, Alessandra, Bianchi, Marco E
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2020
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498322/
https://ncbi.nlm.nih.gov/pubmed/32710624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa613
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