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Gold nanocarriers for transport of oligonucleotides across brain endothelial cells

Treatment of diseases that affect the CNS by gene therapy requires delivery of oligonucleotides to target cells within the brain. As the blood brain barrier prevents movement of large biomolecules, current approaches involve direct injection of the oligonucleotides, which is invasive and may have on...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:PLoS One
Prif Awduron: Fatima, Nayab, Gromnicova, Radka, Loughlin, Jane, Sharrack, Basil, Male, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498062/
https://ncbi.nlm.nih.gov/pubmed/32941446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0236611
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